Search results for "Rhamnus lycioides"

A hypotensive procyanidin-glycoside from Rhamnus lycioides ssp. lycioides.

1990

A lyophilized hot water extract of the aerial parts of Rhamnus lycioides L. (Rhamnaceae) produced a lowering of systemic arterial blood pressure in normotensive anaesthetized Wistar rats. An activity-guided fractionation of the methanolic extract led to the isolation of a tetrameric procyanidin-glycoside which produced a clear dose-dependent hypotensive response (1.5-6 mg/kg i.v.). This principle was characterized using acid hydrolysis, thiolytic degradation and spectroscopic methods. It consisted of four flavanol units with a 2,3-cis configuration and with a O-beta-d-glucosylpyranoside function on the epicatechin terminal unit. The interflavan linkage was (4-8).

Flavonoids ofRhamnus lycioides; Part 2

1988

Flavonoid Constituents of Rhamnus lycioides L.

1986

Abstract From the aerial part of Rhamnus lycioides, which is used in folk medicine in eastern Spain as an antihypertensive drug, seven free flavonoid aglycones were isolated. They were structurally eluci­dated as rhamnazin. rhamnocitrin, isorhamnetin, kaempferol, quercetin. quercetin-3-methylether and taxifolin. by applying the principal spectroscopic methods and TLC with authentic markers.